Table 7.
Univariate Analysis of Prognostic Factors in Patients with GC
| Factors | n | Median Survival Time (Month) | χ2 | P |
|---|---|---|---|---|
| Gender | 0.182 | 0.670 | ||
| Male | 156 | 12.6 | ||
| Female | 74 | 14.0 | ||
| Age (years) | 3.988 | 0.046 | ||
| <60 | 138 | 13.8 | ||
| ≥60 | 92 | 12.4 | ||
| Drinking | 1.424 | 0.233 | ||
| No | 128 | 13.1 | ||
| Yes | 102 | 12.9 | ||
| ECOG performance status | 2.052 | 0.152 | ||
| 0–1 | 148 | 13.0 | ||
| 2 | 82 | 12.8 | ||
| Differentiation degree | 8.169 | 0.004 | ||
| High+medium differentiation | 89 | 14.0 | ||
| Low differentiation | 141 | 12.3 | ||
| TNM staging | 13.690 | <0.001 | ||
| III | 74 | 16.9 | ||
| IV | 156 | 12.3 | ||
| Tumor size (cm) | 0.926 | 0.336 | ||
| <6 | 140 | 13.7 | ||
| ≥6 | 90 | 11.4 | ||
| Tumor site | 3.966 | 0.138 | ||
| Cardia, gastric fundus | 30 | 12.9 | ||
| Corpus ventriculi | 105 | 13.0 | ||
| Gastric antrum, pylorus | 95 | 12.6 | ||
| CEA (ng/mL) | 2.839 | 0.092 | ||
| <5 | 155 | 14.0 | ||
| ≥5 | 75 | 10.9 | ||
| CA199 (kU/L) | 1.004 | 0.316 | ||
| <37 | 143 | 14.1 | ||
| ≥37 | 87 | 12.3 | ||
| Chemotherapy effect | 7.201 | 0.007 | ||
| Sensitive | 87 | 14.8 | ||
| Insensitivity | 143 | 12.1 | ||
| miR-191 | 15.450 | <0.001 | ||
| <1.958 | 115 | 15.8 | ||
| ≥1.958 | 115 | 10.7 | ||
| miR-425 | 9.253 | 0.002 | ||
| <1.667 | 115 | 15.9 | ||
| ≥1.667 | 115 | 10.9 |