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. 2020 Feb 25;15:397–407. doi: 10.2147/COPD.S234760

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© 2020 Wu et al.

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Serum endostatin was correlated with pulmonary function. Serum endostatin was inversely correlated with (A) FEV₁/FVC and (B) FEV₁%pre. After adjusting age, BMI, sex and smoking status, endostatin level was still inversely associated with FEV₁%pre in the stable COPD group (C) and in the total of healthy control and stable COPD (D). The red solid line denotes the line of best fit in stable COPD, the black line represents the line of best fit in a total of healthy control and stable COPD.

Abbreviations: COPD, chronic obstructive pulmonary disease; FEV₁, forced expiratory volume in 1 s; FVC, forced vital capacity.