Fig. 5.

In vitro immunomodulatory profiles of the isolated LAB strains. Cytokine production was evaluated in the supernatants of PBMCs (n=5) different donors stimulated for 24 h by the tested strains and two control strains (B. longum CMUL CXL 001 and E. munditii IAK), in comparison to non-treated cells (NTS). Results indicate levels of (A) IL-10 and (B) IL-12p70. Data represent means ± SEM of 5 independent donors.^*refers to the comparison of bacteria-stimulated PBMCs versus untreated cells; ^*p < 0.05, ^***p < 0.001.