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. 2020 Feb 18;2020:1528362. doi: 10.1155/2020/1528362

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Copyright © 2020 Kun Liu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Experimental process. This course is processed in the N normal group or in the RG108 group. In 3 d: inject DMSO/RG108 for the 3-day group; B: baseline values; S: sham operation; CCI: chronic constrictive injury; d: day; D: death sample taken; HBO: hyperbaric oxygenation; T: intrathecal cathetering; S: sham group; S + H: sham plus HBO group; CCI: CCI group; C + H: CCI plus HBO group; RG108: non-nucleoside DNA methyltransferase inhibitor; −5 d: 5 days before CCI (beginning point of intrathecal cathetering) −3 d: 3 days before CCI (beginning point of drug injection) 6 h: 6 hours after CCI (beginning point of HBO); 1 d, 3 d, 5 d, 7 d, and 14 d: 1, 3, 5, 7, and 14 days after CCI (time points of behavior test). Light blue: behavior test score; pink: surgery; dark blue: HBO treatment; green: injection of DMSO/RG108.