Table 4.
Conditions that mimic SVV.
| Isolated skin vasculitis mimics |
| Purpuric lesions |
| Drug eruptions, erythema multiforme, arthropod bites, infectious emboli (endocarditis), pigmented purpura, cellulitis, viral exanthems, hemorrhagic lesions, scurvy, antiphospholipid syndrome, heparin-induced thrombocytopenia, warfarin necrosis, thrombotic thrombocytopenic purpura, paroxysmal nocturnal hemoglobinuria, amyloidosis |
| Urticarial lesions |
| Urticaria, arthropod bites, serum sickness-like eruption, autoinflammatory diseases, Sweet's syndrome, viral exanthems, Schnitzler's syndrome |
| Nodular lesions |
| Panniculitis, granulomatous diseases, cutaneous neoplasm, superficial phlebitis |
| Ulcers |
| Venous hypertension, peripheral artery disease, pyoderma gangrenosum, calciphylaxis, hypercoagulable diseases, livedoid vasculopathy, chronic infections, hemoglobinopathies |
| Livedo reticularis |
| Paraproteinemia, livedoid vasculopathy, purpura fulminans, hypercoagulable diseases, thrombotic microangiopathies |
| Pulmonary-renal syndrome mimics |
| Infectious disease mimics |
| Severe bacterial pneumonia, postinfectious glomerulonephritis, infective endocarditis, sepsis with multiorgan failure (ARDS and AKI) |
| Cardiac mimics |
| Pulmonary edema with cardiorenal AKI |
| Renal mimics |
| Nephrotic syndrome with pulmonary emboli, microangiopathic diseases |
| Connective tissue diseases |
| Systemic lupus erythematosus, mixed connective tissue disease, systemic sclerosis with scleroderma renal crisis |
| Antiphospholipid syndrome |
| Asthma and eosinophilia (EGPA mimics) |
| Infectious diseases |
| Toxocariasis, HIV, Aspergillus spp. |
| Hematological diseases |
| Hypereosinophilic syndrome, eosinophilic leukemia, systemic mastocytosis, chronic myeloid leukemia |
| Paraneoplastic syndrome |
| Lung cancer, cervical cancer, Hodgkin's lymphoma, non-Hodgkin's T-cell lymphoma |
| Pulmonary diseases |
| Hypereosinophilic asthma, allergic bronchopulmonary aspergillosis, aspirin-exacerbated respiratory disease, idiopathic eosinophilic pneumonia |
| Midline destructive lesions (ENT limited GPA mimics) |
| Cocaine-induced midline destructive lesions |
| Necrotizing sinonasal infections |
| Usual ENT bacteria, mycobacteria, syphilis, fungal, parasitic |
| Neoplastic |
| NK/T-cell lymphoma |
| Inflammatory |
| Sarcoidosis, IgG4-related disease |
| Idiopathic midline destructive disease |