Table 1.
Trend of liver function tests.
| Laboratory value (normal laboratory range and units) | First hospitalization (16 days prior to 2nd admission) | Day 1 second hospitalization (6 days after completing 7-day course of clarithromycin) | Day 2 | Day 3 | Day 4 |
|---|---|---|---|---|---|
| Leukocyte count (3,500–10,100/μL) | 15,000/µL | 12,200/µL | |||
| Hemoglobin (13.5–17.0 g/dL) | 13.6 g/dL | 14.5 g/dL | 5.5 g/dL | ||
| Platelets (150,000–400,000/μL) | 209,000/μL | 129,000/μL | 35,000/μL | ||
| Aspartate aminotransferase (10–37 U/L) | 39 U/L | 499 U/L | 1,119 U/L | 9,470 U/L | 10,820 U/L |
| Alanine aminotransferase (9–47 U/L) | 72 U/L | 539 U/L | 1,110 U/L | 6,420 U/L | 7,210 U/L |
| Alkaline phosphatase (30–110 U/L) | 55 U/L | 127 U/L | 171 U/L | 358 U/L | 202 U/L |
| Albumin (3.5–4.9 g/dL) | 3.5 g/dL | 3.4 g/dL | 3.6 g/dL | 2.9 g/dL | 2.6 g/dL |
| Total bilirubin (0.3–1.2 mg/dL) | 1.0 mg/dL | 1.0 mg/dL | 0.6 mg/dL | 2.3 mg/dL | 1.9 mg/dL |
| Direct bilirubin (0.0–0.4 mg/dL) | NA | NA | NA | 1.8 mg/dL | 1.3 mg/dL |
| INR (0.9–1.2) | NA | 0.9 | >9.0 | >9.0 |
INR, international normalized ratio; NA, not applicable.