Table 2.
HRs (95% CIs) for all-cause mortality across groups of neutrophil percentage-to-albumin ratios.
| NAR | Nonadjusted | Model I | Model II | |||
|---|---|---|---|---|---|---|
| HR (95% CIs) | P value | HR (95% CIs) | P value | HR (95% CIs) | P value | |
| 30-day all-cause mortality | ||||||
| Tertiles | ||||||
| <22.1 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |||
| ≥22.1, <28.1 | 1.35 (1.18, 1.54) | <0.01 | 1.27 (1.11, 1.45) | <0.01 | 1.20 (1.05, 1.38) | 0.01 |
| ≥28.1 | 2.24 (1.99, 2.53) | <0.01 | 2.11 (1.86, 2.39) | <0.01 | 1.48 (1.30, 1.69) | <0.01 |
| P trend | <0.01 | <0.01 | <0.01 | |||
| Quintiles | ||||||
| <19.6 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |||
| ≥19.6, <23.2 | 1.04 (0.87, 1.24) | 0.67 | 0.95 (0.79, 1.14) | 0.58 | 0.97 (0.80, 1.17) | 0.74 |
| ≥23.2, <26.7 | 1.29 (1.09, 1.53) | <0.01 | 1.18 (0.99, 1.40) | 0.06 | 1.13 (0.94, 1.35) | 0.19 |
| ≥26.7, <31.8 | 1.76 (1.49, 2.07) | <0.01 | 1.56 (1.32, 1.84) | <0.01 | 1.33 (1.12, 1.58) | <0.01 |
| ≥31.8 | 2.48 (2.13, 2.90) | <0.01 | 2.29 (1.96, 2.68) | <0.01 | 1.48 (1.25, 1.75) | <0.01 |
| P trend | <0.01 | <0.01 | <0.01 | |||
|
| ||||||
| 90-day all-cause mortality | ||||||
| Tertiles | ||||||
| <22.1 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |||
| ≥22.1, <28.1 | 1.36 (1.22, 1.53) | <0.01 | 1.28 (1.14, 1.43) | <0.01 | 1.21 (1.07, 1.36) | <0.01 |
| ≥28.1 | 2.24 (2.02, 2.49) | <0.01 | 2.10 (1.89, 2.34) | <0.01 | 1.47 (1.31, 1.66) | <0.01 |
| P trend | <0.01 | <0.01 | <0.01 | |||
| Quintiles | ||||||
| <19.6 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |||
| ≥19.6, <23.2 | 1.09 (0.93, 1.27) | 0.27 | 1.00 (0.85, 1.16) | 0.96 | 1.04 (0.89, 1.23) | 0.62 |
| ≥23.2, <26.7 | 1.31 (1.13, 1.52) | <0.01 | 1.19 (1.02, 1.38) | 0.02 | 1.16 (0.99, 1.35) | 0.06 |
| ≥26.7, <31.8 | 1.84 (1.60, 2.12) | <0.01 | 1.63 (1.41, 1.88) | <0.01 | 1.39 (1.20, 1.61) | <0.01 |
| ≥31.8 | 2.50 (2.18, 2.86) | <0.01 | 2.31 (2.01, 2.65) | <0.01 | 1.50 (1.30, 1.74) | <0.01 |
| P trend | <0.01 | <0.01 | <0.01 | |||
|
| ||||||
| 365-day all-cause mortality | ||||||
| Tertiles | ||||||
| <22.1 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |||
| ≥22.1, <28.1 | 1.41 (1.28, 1.56) | <0.01 | 1.31 (1.18, 1.44) | <0.01 | 1.22 (1.10, 1.35) | <0.01 |
| ≥28.1 | 2.18 (1.99, 2.39) | <0.01 | 2.06 (1.88, 2.27) | <0.01 | 1.46 (1.32, 1.62) | <0.01 |
| P trend | <0.01 | <0.01 | <0.01 | |||
| Quintiles | ||||||
| <19.6 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |||
| ≥19.6, <23.2 | 1.11 (0.97, 1.27) | 0.12 | 1.01 (0.88, 1.16) | 0.87 | 1.06 (0.92, 1.22) | 0.41 |
| ≥23.2, <26.7 | 1.34 (1.18, 1.52) | <0.01 | 1.20 (1.06, 1.37) | <0.01 | 1.17 (1.02, 1.33) | 0.03 |
| ≥26.7, <31.8 | 1.83 (1.62, 2.07) | <0.01 | 1.61 (1.42, 1.82) | <0.01 | 1.36 (1.20, 1.55) | <0.01 |
| ≥31.8 | 2.40 (2.13, 2.70) | <0.01 | 2.25 (2.00, 2.54) | <0.01 | 1.49 (1.31, 1.70) | <0.01 |
| P trend | <0.01 | <0.01 | <0.01 | |||
HR: hazard ratio; CI: confidence interval. Models were derived from Cox proportional hazards regression models. Nonadjusted model, adjusted for none. Adjust I model, adjusted for age, ethnicity, and gender. Adjust II model, adjusted for age, ethnicity, gender, acute kidney injury stage, congestive heart failure, atrial fibrillation, liver disease, coronary artery disease, stroke, malignancy, respiratory failure, pneumonia, sodium, potassium, chloride, BUN, INR, APTT, platelet, WBC, hematocrit, creatinine, glucose, bicarbonate, vasopressor use, heart rate, systolic blood pressure, diastolic blood pressure, respiration rate, temperature, SPO2, SOFA, SAPSII, and renal replacement therapy.