Table 2. Predicted risk factors for overall survival in Cox univariate and multivariate analyses.

Factor	Univariate analysis			Multivariate analysis
	HR	95% CI	p-value	HR	95% CI	p-value
Age (year)	1.065	1.055–1.075	< 0.001	1.043	1.030–1.055	< 0.001
Sex (male)	1.051	0.863–1.280	0.623
Ankle brachial pressure index	0.388	0.294–0.513	< 0.001	0.644	0.420–0.985	0.043
Critical limb ischemia	2.708	2.268–3.233	< 0.001	1.374	1.025–1.843	0.034
History of stroke or TIA	1.743	1.441–2.108	< 0.001	1.126	0.867–1.463	0.374
GNRI	0.935	0.927–0.944	< 0.001	0.961	0.948–0.974	< 0.001
eGFR (mL/min/1.73m2)	0.984	0.980–0.988	< 0.001	0.988	0.983–0.993	< 0.001
C-reactive protein (mg/dL)	1.202	1.159–1.247	< 0.001	1.169	1.109–1.233	< 0.001
D-dimer (µg/dL)	1.019	1.011–1.027	< 0.001	1.006	0.994–1.019	0.290
Statin	0.255	0.206–0.316	< 0.001	0.351	0.267–0.462	< 0.001
Aspirin	0.638	0.544–0.748	< 0.001	0.862	0.693–1.071	0.181
Revascularization	0.640	0.545–0.751	< 0.001	0.780	0.551–1.105	0.162

HR: hazard ratio, CI: confidence interval, GNRI: geriatric nutritional risk index, eGFR: estimated glomerular filtration rate.