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Differentially expressed miRNAs in hypoxic and normoxic EVs. (a) Heat map showing clustering of changed miRNAs. Red represents upregulated miRNAs and blue represents downregulated miRNAs; (b) Venn diagram showing the number of overlapped miRNAs in each group; (c) Volcano plot revealing altered miRNAs in hypoxic and normoxic EVs; (d) Bar plot indicating number of altered miRNAs after hypoxia treatment at different P‐values. 
up, 
no_diff, 
down, 
up‐regulated, 
down‐regulated.
