Figure 3.
Knockdown of circ_0007255 diminished cell growth and metastasis in BC cells. (a) QRT‐PCR analysis of circ_0007255 in MB231 and MB468 cells with si‐circ_0007255 and si‐NC transfection was shown. (b) Oxygen consumption ratio was analyzed by Seahorse extracellular flux analyzer in BC cells transfected with si‐circ_0007255 and its control. MB231 () si‐NC and (
) si‐circ_0007255. MB468 (
) si‐NC and (
) si‐circ_0007255. (c) Colony formation was shown in MB231 and MB468 cells under circ_0007255 absence. (d and e) The effect of circ_0007255 deficiency on cell migration and invasion in vitro was shown. Data are presented as mean ± SD of three different experiments. *P < 0.05.