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. 2020 Jan 22;11(3):704–712. doi: 10.1111/1759-7714.13321

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© 2020 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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HSP90B1 expression in lung cancer tissue and prognostic value. (a) HSP90B1 was upregulated in lung cancer tissue compared with normal lung tissue in the Landi dataset (P < 0.0001). (b) HSP90B1 was upregulated in lung large cell carcinoma (LCC), squamous cell carcinoma (SCC) and adenocarcinoma (AD) tissue compared with normal lung tissue in the Hou dataset, respectively (P < 0.001). (c) The Kmplot database was used to confirm the predictive value of HSP90B1 in lung AD, and a high level of HSP90B1 expression was significantly correlated with a worse overall survival [HR = 1.3 (1.03–1.64), P = 0.029] () Hi and () Lo. (d) A high level of HSP90B1 expression was significantly correlated with a worse progression‐free survival in lung AD [HR = 1.45 (1.05–2)，P = 0.024] () Hi and () Lo.

Inline graphic — HSP90B1 expression in lung cancer tissue and prognostic value. (a) HSP90B1 was upregulated in lung cancer tissue compared with normal lung tissue in the Landi dataset (P < 0.0001). (b) HSP90B1 was upregulated in lung large cell carcinoma (LCC), squamous cell carcinoma (SCC) and adenocarcinoma (AD) tissue compared with normal lung tissue in the Hou dataset, respectively (P < 0.001). (c) The Kmplot database was used to confirm the predictive value of HSP90B1 in lung AD, and a high level of HSP90B1 expression was significantly correlated with a worse overall survival [HR = 1.3 (1.03–1.64), P = 0.029] () Hi and () Lo. (d) A high level of HSP90B1 expression was significantly correlated with a worse progression‐free survival in lung AD [HR = 1.45 (1.05–2)，P = 0.024] () Hi and () Lo.