TABLE 3.
HRs and 95% CIs for radiographic progression of knee osteoarthritis according to quartiles of dietary pattern scores1
| Model 12, 3 | Model 23, 4 | |||||||
|---|---|---|---|---|---|---|---|---|
| Cases, n | Person-years | HR (95% CI) | P- value | P-trend | HR (95% CI) | P- value | P- trend | |
| Western5 | ||||||||
| Q1 | 159 | 2550 | 1.00 | Ref | <0.01 | 1.00 | Ref | 0.05 |
| Q2 | 174 | 2547 | 1.13 (0.91, 1.41) | 0.26 | 1.09 (0.88, 1.35) | 0.45 | ||
| Q3 | 199 | 2521 | 1.30 (1.05, 1.61) | 0.02 | 1.23 (0.99, 1.53) | 0.06 | ||
| Q4 | 188 | 2466 | 1.30 (1.05, 1.61) | 0.02 | 1.22 (0.98, 1.51) | 0.08 | ||
| Prudent5 | ||||||||
| Q1 | 203 | 2444 | 1.00 | Ref | 0.02 | 1.00 | Ref | 0.03 |
| Q2 | 172 | 2523 | 0.88 (0.71, 1.08) | 0.23 | 0.90 (0.73, 1.11) | 0.31 | ||
| Q3 | 181 | 2584 | 0.82 (0.67, 1.00) | 0.05 | 0.84 (0.69, 1.03) | 0.09 | ||
| Q4 | 164 | 2533 | 0.79 (0.64, 0.98) | 0.03 | 0.81 (0.66, 1.00) | 0.05 | ||
| Western − prudent5 | ||||||||
| Q1 | 167 | 2550 | 1.00 | Ref | <0.01 | 1.00 | Ref | 0.03 |
| Q2 | 165 | 2585 | 0.96 (0.77, 1.19) | 0.68 | 0.92 (0.74, 1.14) | 0.46 | ||
| Q3 | 194 | 2505 | 1.21 (0.98, 1.49) | 0.07 | 1.16 (0.94, 1.43) | 0.16 | ||
| Q4 | 194 | 2444 | 1.25 (1.01, 1.54) | 0.04 | 1.19 (0.96, 1.47) | 0.12 | ||
JSW, joint space width; KL, Kellgren–Lawrence; NSAID, nonsteroidal anti-inflammatory drug; PASE, Physical Activity Scale for the Elderly; Q, quartile.
Adjusted for age, sex, race (African American, white, other), baseline KL grades 1–3, injury/surgery (yes, no), baseline PASE score, NSAID use (yes, no), and total energy intake (kcal/d, continuous) using a Cox proportional hazards model.
Additional adjustment for income, education, smoking, and alcohol did not significantly alter results.
Additionally adjusted for BMI (<25.0, 25.0–29.9, and ≥30) and weight change from baseline (continuous).
Western pattern: Q1 is more healthy, Q4 is less healthy; prudent pattern: Q1 is less healthy, Q4 is more healthy; Western − prudent pattern: Q1 is more healthy, Q4 is less healthy.