FIGURE 1.

Adjusted HRs for type 2 diabetes events, according to DM-GRS and lifestyle score. In these comparisons, participants with a low DM-GRS and healthy lifestyle serve as the reference group. The participants in the 2 cohorts were pooled and the model was adjusted for sex, age, region, and data sources. There was no evidence of significant interactions between genetic and lifestyle risk factors (P-interaction = 0.60 in the pooled cohort, 0.38 in the CKB, 0.10 in the SCHS). Unadjusted incidence rates are reported per 1000 person-years of follow-up. CKB, China Kadoorie Biobank; DM-GRS, diabetes genetic risk score; SCHS, Singapore Chinese Health Study.