TABLE 1.
Characteristics of the participants at baseline1
| CKB | SCHS | |||
|---|---|---|---|---|
| Characteristic | Participants with genetic data (n = 100,175) | All participants (n = 512,891) | Participants with genetic data (n = 16,172) | All participants (n = 45,411) |
| Age | 51.6 ± 10.8 | 51.5 ± 10.7 | 54.5 ± 7.2 | 55.2 ± 7.6 |
| Male | 42,128 (42.1) | 210,259 (41.0) | 7046 (43.6) | 19,409 (42.7) |
| Smoking | ||||
| Never or occasional smoker | 66,344 (66.2) | 346,773 (67.6) | 11,777 (72.8) | 32,731 (72.1) |
| Ex-smoker | 5854 (5.8) | 30,563 (6.0) | 1568 (9.7) | 4311 (9.5) |
| Current smoker: 1–9 cigarettes/d | 5737 (5.7) | 26,794 (5.2) | 1100 (6.8) | 3387 (7.5) |
| Current smoker: 10–19 cigarettes/d | 7736 (7.8) | 37,138 (7.2) | 1219 (7.5) | 3502 (7.7) |
| Current smoker: ≥20 cigarettes/d | 14,505 (14.5) | 71,623 (14.0) | 508 (3.1) | 1480 (3.3) |
| Alcohol | ||||
| Men: 10–25 g/d; Women: 5–15 g/d | 3277 (3.4) | 17,053 (3.3) | 517 (3.2) | 1447 (3.2) |
| BMI, kg/m2 | 23.4 ± 3.4 | 23.7 ± 3.4 | 23.0 ± 3.4 | 23.0 ± 3.5 |
| Lifestyle score | ||||
| Healthy | 25.0 | 25.2 | 31.5 | 26.5 |
| Intermediate | 36.2 | 36.1 | 33.5 | 30.9 |
| Unhealthy | 38.8 | 38.7 | 35.0 | 42.7 |
| DM-GRS | ||||
| Low | 33.2 | NA | 29.5 | NA |
| Middle | 30.4 | NA | 32.4 | NA |
| High | 36.4 | NA | 38.2 | NA |
1
Values are means ± SDs, n (%), or percentages. The healthy lifestyle is the lowest tertile of lifestyle score. CKB, China Kadoorie Biobank; DM-GRS, diabetes genetic risk score; NA, not available; SCHS, Singapore Chinese Health Study.