Table 3. Reported mortality and morbidity.
| Study | Mortality | Additional factors | Comments | |
|---|---|---|---|---|
| SLTx | BLTx | |||
| Algar | – | – | – | BLTx conferred higher observed perioperative and 1-year mortality rates compared to SLTx |
| Burton | n=228. 30-day perioperative mortality (7.9%) and 90-day perioperative mortality (9.7%) | n=112. 30-day perioperative mortality (3.6%) and 90-day perioperative mortality (10.8%) | – | This was not stratified by indication |
| De Oliveira | 9.40% | 7.70% | Length of hospital stay (days): SLTx, 15 (IQR, 10–25); BLTx, 24 (IQR, 16–48) | P values: mortality difference, 0.46; length of hospital stay, <0.01; readmission, 0.94; length of ICU stay <0.01 |
| Readmission <30 days: SLTx, 21 (25.9%); BLTx, 8 (26.7%) | ||||
| Length of ICU stay: SLTx, 4 (IQR, 3–9); BLTx, 8 (IQR, 6–24) | ||||
| Mason | 30-day perioperative mortality (6%) | 30-day perioperative mortality (6%) | – | – |
| Meyers | In-hospital mortality 9.4% of 32 SLTx patients | In hospital mortality of 7.7% of 13 BLTx patients | Length of hospital stay (days): SLTx, 21 [13–32]; BLTx, 23 [15–39] | P values: difference in hospital mortality is not significant; length of hospital stay was 0.4; length of ICU stay 0.7; mechanical ventilation 0.5 |
| Intensive care unit stay (days): SLTx, 5 [3–10]; BLTx, 6 [4–12] | ||||
| Mechanical ventilation (days): SLTx, 3 [2–9]; BLTx, 4 [3–18] | ||||
| Wei | – | – | Post-operative ICU days (mean ± SD): SLTx, 5.8±6.3; BLTx, 4.6±2.8 P value for: post-op length of stay was 0.014; post-op ICU stay 0.551 |
30-day mortality was higher in BLTx but not statistically significant based on the Mantel Haenzel log rank test (P=0.131) |
| Post-operative length of stay in days (mean ± SD): 49.8±33.0; 33.1±25.2 | The difference in the number of complications including primary graft dysfunction, pulmonary bacterial infection, anastomotic complications, heart failure, arrhythmia, acute kidney injury and malignant tumour was not significant between SLTx vs. BLTx | |||
| Neurohr | – | – | – | Increased 90-day mortality in SLTx without difference reaching statistical significance (P=0.06) |
SLTx, single lung transplantation; BLTx, bilateral lung transplantation; IQR, interquartile range; ICU, intensive care unit; SD, standard deviation.