Table 2.

PKs of CHMFL-VEGFR2-002 and sunitinib.

Parameter	CHMFL-VEGFR2-002		Sunitinib
	i.v. (1 mg/kg)	p.o. (10 mg/kg)	i.v. (1 mg/kg)	p.o. (10 mg/kg)
AUC0–t (ng/mL·h)	443.292 ± 36.858	2194.607 ± 759.148	142.7 ± 40.3	927.2 ± 107.5
AUC0–∞ (ng/mL·h)	452.771 ± 34.465	2265.7 ± 692.912	144.8 ± 39.6	1095.9 ± 96.7
MRT0–t (h)	0.956 ± 0.18	4.156 ± 1.338	0.98 ± 0.04	7.63 ± 0.30
Cmax (ng/mL)	1331.896 ± 525.603	455.579 ± 17.611	236.0 ± 66.8	175.0 ± 21.7
Tmax (h)	0.017 ± 0	0.5 ± 0	0.33 ± 0	1.25 ± 1.06
t1/2 (h)	2.416 ± 0.952	2.931 ± 0.614	1.05 ± 0.34	1.38 ± 0.46
F (%)	–	49.51	–	75.7

− Not applicable.