. 2019 Oct 18;10(3):488–497. doi: 10.1016/j.apsb.2019.10.004

Table 3.

Acute toxicity test of CHMFL-VEGFR2-002 and sunitinib.

Compd.	Dosage (mg/kg)	Concentration (mg/mL)	Volume (mL/mouse)	Number of deaths (death/total)
Vehicle (HKI)	0	0	0.2	♀: 0/2
CHMFL-VEGFR2-002	2000	200	0.2	♀: 0/2
	1000	100	0.2	♀: 0/2
	500	50	0.2	♀: 0/2
	250	25	0.2	♀: 0/2
	125	12.5	0.2	♀: 0/2
Sunitinib	2000	200	0.2	♀: 2/2
	1000	100	0.2	♀: 0/2
	500	50	0.2	♀: 0/2
	250	25	0.2	♀: 0/2
	125	12.5	0.2	♀: 0/2