Table 2.
Trend of Available Liver Tests Related to Nonsteroidal SARM Use for Case 2
| Case 2 | |||||
|---|---|---|---|---|---|
| Time line | ALT, U/L (<40) | AST, U/L (<40) | ALP, U/L (30‐110) | Bilirubin, μmol/L (2‐20) | Comment |
| Baseline | 24 | 21 | 57 | 10 | 8 months prior |
| −2 weeks | 200 | 111 | 111 | 80 | Ordered by primary care physician for pruritus; referred to hepatologist; SARM use had ceased after intermittent use for months |
| Initial review by hepatologist | 54 | 63 | 327 | 291 | |
| 2 weeks | 51 | — | 299 | 321 | |
| 3 weeks | 44 | 61 | 286 | 346 | |
| 4 weeks | 60 | 65 | 262 | 187 | |
| 8 weeks | 172 | 123 | 121 | 32 | |
| 12 months | 27 | — | 59 | 7 | |