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. 2020 Jan 20;48(5):e30. doi: 10.1093/nar/gkaa017

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Performance of PG-RCA and CIRI in diluted FBS samples. Real-time changes of (1–10 Hz) are recorded for (A) PG-RCA of 100 fM target DNA and (B) cleavage of MNP clusters by preformed Cas12a ternary complexes. Final concentrations of FBS are indicated in panels. Independent replicates (n = 3) are plotted in the same color. Red curves in panel (B) are from Figure 2B for reference.

Inline graphic — Performance of PG-RCA and CIRI in diluted FBS samples. Real-time changes of (1–10 Hz) are recorded for (A) PG-RCA of 100 fM target DNA and (B) cleavage of MNP clusters by preformed Cas12a ternary complexes. Final concentrations of FBS are indicated in panels. Independent replicates (n = 3) are plotted in the same color. Red curves in panel (B) are from Figure 2B for reference.