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. 2019 Dec 26;5(1):61–72. doi: 10.1002/epi4.12373

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© 2019 The Authors. Epilepsia Open published by Wiley Periodicals Inc. on behalf of International League Against Epilepsy.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Subtraction ictal SPECT coregistered to MRI (SISCOM) imaging. Relative ictal hyperperfusion (+2 to +4 SD) is identified in red‐yellow, while the relative ictal hypoperfusion zones are colored in blue (−2 to −4 SD). Notice the localized zone of relative hyperperfusion in the right anteromesial temporal lobe (yellow), with propagation to the superior lateral temporal neocortex (red), while the contralateral anteromesial temporal lobe shows a light hypoperfusion (light‐blue). The patient reached complete seizure freedom after resective surgery, which confirmed the presence of a focal cortical dysplasia type IIA in the right anterior temporal lobe (patient #39)