Table 3.
Effects of the extracts and fractions of celery seeds on inhibition of HSC-LX2 cell proliferation (mean ± SD, n = 3).
| Group | Fraction | Dose (μg·mL−1) | OD | Inhibition ratio (%) |
|---|---|---|---|---|
| Solvent control | — | 0.254 ± 0.019 | — | |
| Blank control | 0 | 1.021 ± 0.079 | — | |
| Model group (TGF-β1) | 0.1 | 3.522 ± 0.178## | — | |
| BJRG | 50 | 1.116 ± 0.012∗∗ | 73.11 ± 0.87 | |
|
| ||||
| Aqueous extract of celery seeds | 50 | 3.532 ± 0.227## | — | |
| 100 | 3.074 ± 0.131∗## | 13.79 ± 2.91 | ||
| 200 | 2.537 ± 0.541∗# | 30.13 ± 1.02 | ||
|
| ||||
| 95% ethanol extract of celery seeds | 50 | 3.602 ± 0.281 | — | |
| 100 | 2.926 ± 0.0526∗# | 18.22 ± 1.69 | ||
| 200 | 1.717 ± 0.026∗∗# | 55.22 ± 2.44 | ||
|
| ||||
| 60% ethanol extract of celery seeds | 50 | 2.123 ± 0.138∗∗# | 42.75 ± 2.21 | |
| 100 | 1.351 ± 0.052∗∗ | 66.42 ± 1.53 | ||
| 200 | 1.097 ± 0.022∗∗ | 74.20 ± 2.38 | ||
| PP | 25 | 2.598 ± 0.224∗# | 28.26 ± 1.29 | |
| 50 | 1.619 ± 0.129∗∗# | 58.21 ± 2.11 | ||
| 75 | 1.066 ± 0.023∗∗ | 75.14 ± 1.45 | ||
| PE | 25 | 2.893 ± 0.159∗# | 19.23 ± 1.32 | |
| 50 | 2.001 ± 0.239∗∗# | 46.55 ± 3.87 | ||
| 75 | 1.119 ± 0.312∗∗ | 73.52 ± 2.36 | ||
| PB | 25 | 2.956 ± 0.239∗# | 17.30 ± 3.13 | |
| 50 | 1.916 ± 0.209∗∗# | 49.24 ± 2.03 | ||
| 75 | 1.754 ± 0.241∗∗# | 54.09 ± 1.44 | ||
| PW | 25 | 3.369 ± 0.319## | 4.68 ± 0.75 | |
| 50 | 2.889 ± 0.162∗# | 19.36 ± 1.72 | ||
| 75 | 2.105 ± 0.311∗∗# | 43.36 ± 3.55 | ||
Compared with the blank control group (#P < 0.05, ##P < 0.01); compared with the model group (∗P < 0.05, ∗∗P < 0.01).