Table 6.
Effects of monomeric compounds on the proliferation of HSC-LX2 cells (mean ± SD, n = 3).
| Group | Dose (μg·mL−1) | OD | Inhibition ratio (%) |
|---|---|---|---|
| Solvent control | — | 0.164 ± 0.012 | — |
|
| |||
| Blank control | 0 | 1.210 ± 0.070 | — |
|
| |||
| Model group(TGF-β1) | 0.1 | 3.325 ± 0.138## | — |
|
| |||
| BJRG | 60 | 0.939 ± 0.104∗∗ | 75.46 ± 2.11 |
|
| |||
| Apigenin | 15 | 2.746 ± 0.167∗# | 18.33 ± 1.48 |
| 30 | 1.816 ± 0.046∗∗# | 47.72 ± 1.93 | |
| 60 | 1.071 ± 0.107∗∗ | 71.32 ± 2.41 | |
|
| |||
| 5-Methoxypsoralen | 15 | 3.337 ± 0.128 | — |
| 30 | 3.382 ± 0.130 | — | |
| 60 | 3.454 ± 0.117 | — | |
|
| |||
| Apiin | 15 | 3.238 ± 0.177## | 2.73 ± 0.06 |
| 30 | 2.716 ± 0.184∗# | 19.26 ± 1.30 | |
| 60 | 2.349 ± 0.329∗# | 30.87 ± 1.85 | |
|
| |||
| Rutin | 15 | 3.412 ± 0.193 | — |
| 30 | 3.201 ± 0.104## | 3.92 ± 0.57 | |
| 60 | 2.825 ± 0.184∗## | 15.81 ± 2.68 | |
|
| |||
| Kaempferol | 15 | 3.462 ± 0.161 | — |
| 30 | 3.186 ± 0.252## | 4.38 ± 1.02 | |
| 60 | 2.629 ± 0.177∗# | 22.02 ± 3.93 | |
|
| |||
| Luteolin | 15 | 3.329 ± 0.202 | — |
| 30 | 3.341 ± 0.175 | — | |
| 60 | 3.420 ± 0.330 | — | |
|
| |||
| Quercetin | 15 | 3.186 ± 0.268## | 4.39 ± 0.75 |
| 30 | 2.337 ± 0.224∗# | 31.26 ± 2.11 | |
| 60 | 1.798 ± 0.218∗∗# | 48.28 ± 2.74 | |
|
| |||
| Mollugin | 15 | 3.348 ± 0.152 | — |
| 30 | 3.350 ± 0.183 | — | |
| 60 | 3.425 ± 0.159 | — | |
|
| |||
| Butylphthalide | 15 | 3.029 ± 0.249## | 9.36 ± 1.01 |
| 30 | 2.366 ± 0.048∗# | 30.33 ± 2.77 | |
| 60 | 1.367 ± 0.164∗∗ | 61.93 ± 3.51 | |
|
| |||
| Aesculetin | 15 | 2.426 ± 0.245∗# | 28.44 ± 4.01 |
| 30 | 1.979 ± 0.122∗∗# | 42.55 ± 3.14 | |
| 60 | 1.277 ± 0.273∗∗ | 64.90 ± 4.21 | |
Compared with the blank control group (#P < 0.05, ##P < 0.01); compared with the model group (∗P < 0.05, ∗∗P < 0.01).