Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 15;27(8):1546–1561. doi: 10.1016/j.bmc.2019.02.051

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Scheme 1 — Reagents and conditions: (i) EtOH, r.t., o/n (ii) NaBH₄, MeOH, r.t., 4 h (iii) Et₃N, 2,3-dibromopropionic acid ethyl ester, toluene, 80 °C, o/n (iv) LiAlH₄, THF, r.t., o/n (v) SOCl₂, CH₂Cl₂, r.t., 48 h (vi) (a) Imidazole, K₂CO₃, CH₃CN, 45 °C, 1 h (b) chloride 7, 70 °C, 48 h.