Table 4.

Overall and progression-free survival

	6-week schedule (n = 82)	5-week schedule (n = 36)	Total (n = 118∗)
Median follow-up, mo	51.8	26.4	50.0
OS
Events, deaths	52	19	71
1-year OS (95% CI), %	87.8 (80.7-94.9)	71.4 (56.3-86.5)	82.9 (76.0-89.8)
2-year OS (95% CI), %	68.3 (58.3-78.3)	49.8 (32.7-66.9)	62.9 (54.1-71.7)
Median OS (95% CI), mo	41.2 (28.5-53.9)	22.1 (12.9-31.3)	37.5 (26.1-48.8)
6- vs 5-week HR (95% CI)	0.56 (0.32-0.98)
P value	.04
PFS
Events, progressions/deaths	57	27	84
1-year PFS (95% CI), %	70.7 (60.9-80.5)	44.4 (28.1-60.7)	62.7 (53.9-71.5)
2-year PFS (95% CI), %	48.8 (38.0-59.6)	30.6 (15.5-45.7)	43.2 (34.2-52.2)
Median PFS (95% CI), mo	21.1 (10.9-31.2)	8.0 (2.2-13.9)	16.0 (8.7-23.2)
6- vs 5-week HR (95% CI)	0.53 (0.33-0.86)
P value	.01

Abbreviations: CI = confidence interval; HR = hazard ratio; OS = overall survival; PFS = progression-free survival.

^∗Of 120 patients recruited, 118 began treatment.