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. 2020 Jan 20;44(4):395–402. doi: 10.5114/ceji.2019.92795

Table 2.

Differences in the proportion of macrophage subpopulations depending on the distance from the tumour, on the basis of bronchoalveolar lavage fluid (BAL) analysis from the lung affected by cancer (clBALF) and from the healthy symmetrical lung (hlBALF) as a control from the same patient

Parameter clBALF hlBALF p
Macrophages (%) Median (p25-p75) Median (p25-p75)
1 CCR7+ 0.7 (0.0-2.6) 6.0 (0.8-18.2)
2 CD163+ 12.4 (7.7-23.6) 7.7 (2.4-32.5)
3 CCR7+CD163+ 84.6 (64.7-90.6) 51.9 (34.9-83.3) 0.0496*
4 CCR7lowCD163+ 92.9 (84.0-97.4) 56.0 (48.0-70.6) 0.0194*
5 CCR7+CD163low 7.8 (0.0-12.1) 40.2 (18.7-56.8) 0.0007*

The populations in rows 1, 2, and 3 are presented as the proportion of all macrophages in five areas of view. Rows 4 and 5 present “subgroups” of 3. Data expressed as median proportion (p25-p75); clBALF – bronchoalveolar lavage fluid from the lung affected by cancer, hlBALF – bronchoalveolar lavage fluid from the healthy lung, * p < 0.05