Table 1.
Clinicopathological details for DCIS and invasive cancer patients
|
DCIS (n = 76) n (%)a |
Invasive cancer (n = 248) n (%)a |
|
|---|---|---|
| Age(years)b | 60 (32‐79) | 59 (24‐84) |
| Presentation | ||
| Symptomatic | 7 (12) | 73 (31) |
| Screening | 49 (88) | 166 (69) |
| Invasive cancer pathologyc | ||
| Invasive ductal | 219 (90) | |
| Invasive lobular | 21 (9) | |
| Other | 3 (1) | |
| Tumour size, mm | ||
| Mean (range) | 31.7 (1‐150) | 16.4 (1‐70) |
| Gradec (DCIS/ invasive) | ||
| Low/1 | 1 (1) | 63 (26) |
| Intermediate/2 | 18 (25) | 104 (42) |
| High/3 | 54 (74) | 78 (32) |
| ER statusc | ||
| Positive | 50 (68) | 202 (82) |
| Negative | 23 (32) | 44 (18) |
| PR statusc | ||
| Positive | 41 (56) | 170 (69) |
| Negative | 32 (44) | 76 (31) |
| Microinvasionc | ||
| Yes | 6 (9) | |
| No | 65 (81) | |
| HER2 receptor statusc | ||
| Positive | 27 (11) | |
| Negative | 219 (89) | |
| Ki67 expressionc | ||
| <20% | 130 (55) | |
| >20% | 105 (45) | |
| Lymph node statusc | ||
| Positive | 68 (28) | |
| Negative | 177 (72) | |
| Disease recurrence | ||
| Yes | 13 (5.2) | |
| No | 233 (94.8) | |
| Disease free survival (years) | ||
| Mean (95% CI) | 59.7 years (1.8‐76.8) | |
| Died during follow up | ||
| Yes | 15 (6) | |
| No | 231 (94) | |
| Overall survival (years) | ||
| Mean (95% CI) | 61.7 years (8.4‐80.2) | |
a
Unless otherwise stated
b
Median (range)
c
Data unavailable on some patients;