Table 4.
Mortality risks of the leading noncancer causes of death by cancer sites in Korea
| Cancer site | Men | Women | ||||||
|---|---|---|---|---|---|---|---|---|
| COD | Count | SMR [95% CI]a | AER [95% CI]b | COD | Count | SMR [95% CI]a | AER [95% CI]b | |
| Stomach | Heart diseases (I20‐I51)COD1 | 1 196 | 0.92 [0.87, 0.98] | −1.45 [−2.87, −0.02] | Cerebrovascular diseases (I60‐I69)COD1 | 446 | 0.99 [0.90, 1.09] | −0.07 [−1.79, 1.65] |
| Intentional self‐harm (X60‐X84)SMR1 | 864 | 1.68 [1.57, 1.79] | 5.10 [4.04, 6.16] | Intentional self‐harm (X60‐X84)SMR1 | 149 | 1.74 [1.46, 2.02] | 1.86 [0.98, 2.74] | |
| Colorectal | Heart diseases (I20‐I51)COD1 | 735 | 0.74 [0.69, 0.80] | −4.98 [−6.58, −3.38] | Heart diseases (I20‐I51)COD1 | 372 | 0.80 [0.72, 0.89] | −2.72 [−4.41, −1.02] |
| Intentional self‐harm (X60‐X84)SMR1 | 537 | 1.40 [1.28, 1.52] | 3.01 [1.84, 4.18] | Intentional self‐harm (X60‐X84)SMR1 | 136 | 1.59 [1.32, 1.85] | 1.51 [0.63, 2.38] | |
| Liver | Viral hepatitis (B15‐B19)COD1, SMR1 | 330 | 46.71 [41.67, 51.75] | 18.02 [16.01, 20.03] | Viral hepatitis (B15‐B19)COD1, SMR1 | 111 | 56.44 [45.94, 66.94] | 18.78 [15.20, 22.37] |
| Lung | Heart diseases (I20‐I51)COD1 | 368 | 1.10 [0.99, 1.21] | 2.20 [−1.22, 5.62] | Heart diseases (I20‐I51)COD1 | 113 | 1.03 [0.84, 1.22] | 0.36 [−3.13, 3.85] |
| Intentional self‐harm (X60‐X84)SMR1 | 365 | 2.99 [2.69, 3.30] | 16.01 [13.16, 18.85] | Intentional self‐harm (X60‐X84)SMR1 | 59 | 2.79 [2.08, 3.50] | 4.52 [2.42, 6.61] | |
| Breast | Heart diseases (I20‐I51)COD1 | 246 | 0.91 [0.79, 1.02] | −0.35 [−0.97, 0.28] | ||||
| Intentional self‐harm (X60‐X84)SMR1 | 225 | 1.66 [1.44, 1.88] | 1.25 [0.73, 1.77] | |||||
| Prostate | Heart diseases (I20‐I51)COD1 | 369 | 0.69 [0.63, 0.75] | −9.54 [−12.41, −6.67] | ||||
| Intentional self‐harm (X60‐X84)SMR1 | 252 | 1.10 [0.96, 1.23] | 0.91 [−0.84, 2.67] | |||||
| Thyroid | Heart diseases (I20‐I51)COD1, SMR1 | 83 | 0.57 [0.45, 0.69] | −2.60 [−3.84, −1.36] | Heart diseases (I20‐I51)COD1 | 212 | 0.63 [0.54, 0.71] | −1.04 [−1.42, −0.66] |
| Intentional self‐harm (X60‐X84)SMR1 | 163 | 0.73 [0.62, 0.84] | −0.50 [−0.82, −0.19] | |||||
Patients under 20 y old and over 85 y old at the midpoint of their death year were excluded. Causes of death were classified according to the 56 causes of death classification by the Statistics Korea. ICD‐10 codes for causes of death are in parentheses. Cancer patients diagnosed from 2000 to 2016 and followed up to 31 December 2016 and cause of death of cancer patients from 2012 to 2016.
Abbreviations: 95% CI, 95% Confidence Interval; AER, absolute excess risk; COD, cause of death; SMR, standard mortality ratio.
COD1: Top ranked by the proportion of noncancer causes of death. SMR1: Top ranked by the SMR.
SMRs for the specific cause of death were calculated as the ratio of total observed deaths in cancer patients from 2012 to 2016 to the expected deaths in the general population from 2012 to 2016, respectively.
Absolute excess risk(AER) was calculated as the difference between expected rate and observed rate per 10 000 person‐years.