Table 3.
Comparison of C‐indexes for the nomograms and TNM staging system in patients with breast cancer
| Items | BCSS | OS | ||
|---|---|---|---|---|
| C‐index (95% CI) | P value | C‐index (95% CI) | P value | |
| Nomogram 1 | 0.835 (0.832‐0.838) | Reference | 0.773 (0.771‐0.776) | Reference |
| TNM staging system | 0.782 (0.779‐0.786) | <.001 | 0.676 (0.673‐0.679) | <.001 |
| Nomogram 2 (excluding race) | 0.834 (0.831‐0.837) | .356 | 0.772 (0.769‐0.775) | .253 |
| Nomogram 3 (excluding all clinicopathological factors)† | 0.715 (0.711‐0.719) | <.001 | 0.701 (0.698‐0.703) | <.001 |
| Nomogram 4 (excluding all therapy information) ‡ | 0.832 (0.830‐0.835) | .165 | 0.768 (0.766‐0.771) | .002 |
| Nomogram 5 (excluding all socioeconomic factors) § | 0.832 (0.829‐0.835) | .148 | 0.766 (0.763‐0.769) | <.001 |
Abbreviations: BCSS, breast cancer‐specific survival; CI, confidence interval; ER, estrogen receptor; OS, overall survival; PR, progesterone receptor.
†Clinicopathological factors include histology, grade, tumor size, number of positive lymph nodes, ER status and PR status.
‡Therapy information include surgery, chemotherapy and radiation.
§Socioeconomic factors include marital status, insurance, residence, median household income and education level.