Fig. 5.

AMPK may be involved in DNA repair via the NHEJ pathway. A, TAP-MS analysis of Artemis. The list of Artemis-interacting proteins is shown, which was identified by TAP-MS using Artemis as the bait. The PSM numbers are the average of the two repeats. B, HEK293A Artemis knockout cells were validated using Western blot analysis. C, D, Clonogenic survival assays. C, Images of the clonogenic survival assay results. D, Quantification and statistical analysis of clonogenic survival assay results. Clonogenic survival assays were performed using at least three biological replicates, and a statistical analysis was performed using Student's t test.