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. 2019 Dec 17;19(3):444–455. doi: 10.1074/mcp.RA119.001626

Table I. Significantly regulated proteins that are more abundant in low-quality human spermatozoa following Percoll density gradient separation.

Uniprot Accession # Gene name Protein Name Log2 Fold Change p value
P27487 DPP4 Dipeptidyl peptidase 4 -5.20 6.01E-06
O00468 AGRN Agrin -4.82 5.30E-05
P54107 CRISP1 Cysteine-rich secretory protein 1 -4.44 0.004512
P35052 GPC1 Glypican-1 -3.78 0.000514
P11388 TOP2A DNA topoisomerase 2-alpha -3.61 0.000816
Q7Z6Z7 HUWE1 E3 ubiquitin-protein ligase HUWE1 -3.50 0.00303
P26641 EEF1G Elongation factor 1-gamma -3.26 0.000194
P26640 VARS Valine–tRNA ligase -3.25 0.000107
P04083 ANXA1 Annexin A1 -3.23 0.001318
P02751 FN1 Fibronectin -3.067 0.003391
Q8IX12 CCAR1 Cell division cycle and apoptosis regulator protein 1 -3.01 0.012372
Q15046 KARS Lysine–tRNA ligase -2.97 6.36E-05
P15144 ANPEP Aminopeptidase N -2.82 0.004911
P29692–2 EEF1D Isoform 2 of Elongation factor 1-delta -2.69 0.000117
P26583 HMGB2 High mobility group protein B2 -2.59 0.03805
P30101 PDIA3 Protein disulfide-isomerase A3 -2.58 0.000584
P06748 NPM1 Nucleophosmin -2.52 0.003851
P24534 EEF1B2 Elongation factor 1-beta -2.49 0.003658
Q5BJF6–7 ODF2 Isoform 7 of Outer dense fiber protein 2 -2.47 0.00268
O95473 SYNGR4 Synaptogyrin-4 -2.31 0.015401
P49913 CAMP Cathelicidin antimicrobial peptide -2.25 0.005459
P30084 ECHS1 Enoyl-CoA hydratase, mitochondrial -2.24 0.001973
Q04837 SSBP1 Single-stranded DNA-binding protein, mitochondrial -2.12 0.007349
P07355–2 ANXA2 Isoform 2 of Annexin A2 -2.09 0.035633
P14923 JUP Junction plakoglobin -2.08 0.015926
P39023 RPL3 60S ribosomal protein L3 -2.01 0.000688