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. 2020 Mar 2;4:19. doi: 10.1186/s41927-020-0118-z

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© The Author(s) 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Physician-reported reasons given for patient switching from 1st to 2nd line TNFi. * Secondary lack of efficacy: loss of response over time; † I wanted to use bDMARD that can be used as a monotherapy; ‡ I wanted to use a bDMARD that can be used in combination. MOA: Mode of action; bDMARD: biologic Disease Modifying Anti Rheumatic Drug