Table 1.
Demographic characteristics and laboratory results of the study cohorts
| CAE | CAD | CON | p value | CAE vs CAD | CAE vs CON | CAD vs CON | |
|---|---|---|---|---|---|---|---|
| Number of patients | 30 | 30 | 30 | ||||
| Age (year) | 57.37 ± 13.82 | 60.8 ± 10.84 | 56.03 ± 10.15 | 0.272 | |||
| Sex (Female, %) | 20.0 | 33.3 | 16.7 | 0.271 | |||
| Hypertension (%) | 60.0 | 73.3 | 43.3 | 0.061 | |||
| DM (%) | 16.7 | 33.3 | 10 | 0.067 | |||
| Smokers (%) | 46.7 | 46.7 | 46.7 | 1.000 | |||
| Alcohol consumption (%) | 16.7 | 16.7 | 26.7 | 0.535 | |||
| Family history of CAD (%) | 6.7 | 6.7 | 16.7 | 0.329 | |||
| Systolic Blood Pressure (mmHg) | 132.27 ± 18.52 | 129.03 ± 19.12 | 129.57 ± 17.34 | 0.766 | |||
| Diastolic Blood Pressure (mmHg) | 78.73 ± 13.48 | 74.33 ± 12.12 | 72.10 ± 11.90 | 0.119 | |||
| Heart rate (bpm) | 72.90 ± 12.10 | 70.63 ± 9.17 | 69.93 ± 10.47 | 0.532 | |||
| BMI (kg/m2) | 26.99 ± 3.96 | 25.36 ± 2.73 | 25.78 ± 2.73 | 0.127 | |||
| ALT† (U/L) | 26(16.75–46.25) | 28.5(19.75–37) | 22.5(16.75–29.5) | 0.336 | |||
| Creatinine (μmol/L) | 136.69 ± 233.97 | 79.73 ± 17.15 | 77.5 ± 12.16 | 0.166 | |||
| LDL-C (mmol/L) | 2.34 ± 0.75 | 2.15 ± 0.70 | 2.48 ± 0.61 | 0.185 | |||
| WBC# (109cell/L) | 6.89 ± 2.25 | 6.92 ± 1.91 | 6.59 ± 1.58 | 0.769 | |||
| Neut# (109cell/L) | 5.49 ± 2.57 | 4.36 ± 1.52 | 5.77 ± 9.28 | 0.593 | |||
| HGB (g/L) | 141.07 ± 21.56 | 135.5 ± 13.95 | 148.63 ± 15.93 | 0.017* | 0.557 | 0.333 | 0.004* |
| PLT (109cell/L) | 211.57 ± 65.15 | 202.73 ± 63.25 | 225.57 ± 53.33 | 0.346 | |||
| MPXI | 1.02 ± 3.01 | 3.22 ± 3.03 | 3.52 ± 4.25 | 0.013* | 0.016* | 0.007* | 0.745 |
| Markis classification | |||||||
| Type 1 | 10(33.3%) | ||||||
| Type 2 | 5(16.7%) | ||||||
| Type 3 | 11(36.7%) | ||||||
| Type 4 | 4(13.3%) | ||||||
| Ecatatic Coronary artery | |||||||
| Left anterior descending | 19(63.3%) | ||||||
| Left circumflex | 14(46.7%) | ||||||
| Right | 16(53.3%) | ||||||
Pearson’s chi-square test was used for frequency differences between categories. ANOVA or Kruskal-Wallis H test (†) was used for continuous variables, LSD or Dunnett T3 was used for multiple comparisons
CAE Coronary artery ectasia, CAD Coronary artery disease, CON Normal coronary artery group, DM Diabetes mellitus, BMI Body mass index, ALT Alanine aminotransferase, LDL-C Low-density lipoprotein-cholesterol, MPO Myeloperoxidase, MPXI Intra-neutrophil mean MPO index, WBC# White blood cell, Neut# Neutrophil leucocyte count, HGB Hemoglobin, PLT Platelet count
*Statistically significant