Table 1.
Demographic and clinical baseline data for the patients
| 2017 (n = 42) | 2018 (n = 15) | Total (n = 57) | p value | |
|---|---|---|---|---|
| Number (%) | Total | |||
| Gender | ||||
| Male (n = 46) | 35 (83.3) | 11 (73.3) | 46 (80.7) | |
| Female (n = 11) | 7 (16.7) | 4 (26.7) | 11 (19.3) | |
| Age (median; IQR) | 54 (42–62) | 52 (45–62) | 53 (43–62) | 0.792 |
| Major diagnosis on ICU admission | ||||
| Chronic liver disease (CLD) | 27 (64) | 10 (67) | 37 (65) | |
| Acute liver failure (ALF) | 3 (7) | 1 (7) | 4 (7) | |
| Acute on chronic liver failure (ACLF) | 7 (17) | 2 (13) | 9 (16) | |
| Dengue hepatitis | 1 (2) | 0 | 1 (2) | |
| Hepatic venous outflow tract obstruction (HVOTO) | 0 | 1 (7) | 1 (2) | |
| Pancreatitis | 3 (7) | 0 | 3 (5) | |
| Functional metastatic pancreatic neuroendocrine tumor | 1 (2) | 0 | 1 (2) | |
| Chronic subdural hemorrhage | 0 | 1 (7) | 1 (2) | |
| Comorbidity | ||||
| Diabetes mellitus | 9 (21) | 7 (47) | 16 (28) | 0.094 |
| Hypertension | 2 (5) | 4 (27) | 6 (11) | 0.036 |
| Acute kidney injury | 36 (86) | 13 (87) | 49 (86) | 1.00 |
| Chronic kidney disease | 3 (7) | 1 (7) | 4 (7) | 1.00 |
| Hepatic encephalopathy | 34 (81) | 9 (60) | 43 (75) | 0.161 |
| Symptoms | ||||
| Fever during IWP | 10 (24) | 3 (20) | 13 (23) | 1.00 |
| Clinical data (median; IQR) | ||||
| TLC | 7.6 (6.1–12.1) | 10 (5.2–14.3) | 8.5 (6.0–13.1) | 0.568 |
| HB | 8.7 (7.5–10.3) | 8.7 (8–10.2) | 8.7 (7.6–10.3) | 0.913 |
| Creatinine | 1.2 (0.8–2.5) | 1.3 (0.8–1.7) | 1.3 (0.8–2.1) | 0.978 |
| Total bilirubin | 5.7 (2.6–9.9) | 4.4 (2.4–8) | 5.5 (2.2–9.8) | 0.337 |
| Aspartate aminotransferase | 64 (49–153) | 58 (39–89) | 64 (48–105) | 0.145 |
| Alanine aminotransferase | 32 (22–65) | 27 (21–47) | 32 (21–55) | 0.281 |
| Alkaline phosphatase | 100 (68–130) | 100 (73–136) | 100 (71–131) | 0.935 |
| Gamma-glutamyl transferase | 32 (19–54) | 59 (36–135) | 41 (21–63) | 0.026 |
| Albumin | 3.9 (2.5–4.3) | 2.5 (2.4–3.2) | 2.5 (2–2.9) | 0.167 |
| Globulin | 3.7 (3.4–4.0) | 3.6 (3.1–3.9) | 3.5 (2.9–4.3) | 0.650 |
| INR | 1.7 (1.5–2.2) | 1.7 (1.6–2.1) | 1.7 (1.5–2.2) | 0.731 |
| Procalcitonin | 1 (0.25–1.7) | 0.7 (0.9–1.2) | 0.93 (0.2–1.3) | 0.257 |