Table 2.
Renal histological qualitative parameters affected by ischemia (ISC) and acacetin (Aca) treatment or both in male mice
| Histopathology Indices | ||||||
|---|---|---|---|---|---|---|
| Groups | Intra-cellular vacuolization | Tubular dilatation | Vascular congestion | Intra-tubular proteinaceous casts | Tubular cell detachment | Total |
| Control | 0 | 0 | I | 0 | 0 | 1 |
| Sham operation | 0 | 0 | I | 0 | 0 | 1 |
| Ischemia | IV | IV | IV | XII | VII | 31** |
| Sham Aca 10 | 0 | 0 | I | 0 | 0 | 1aab≠≠ |
| Sham Aca 25 | 0 | 0 | I | 0 | 0 | 1aab≠≠ |
| Sham Aca 50 | 0 | 0 | I | 0 | 0 | 1aa≠≠ |
| Control Aca 10 | 0 | 0 | I | 0 | 0 | 1*≠≠ |
| Control Aca 25 | 0 | 0 | I | 0 | 0 | 1aab≠≠ |
| Control Aca 50 | 0 | 0 | I | 0 | 0 | 1aab≠≠ |
| ISC+Aca 10 | II | III | IV | III | III | 15**≠ |
| ISC+Aca 25 | 0 | II | II | 0 | II | 6a*≠≠ |
| ISC+Aca 50 | 0 | 0 | I | 0 | I | 2aab≠≠ |
*p<0.05, **p<0.01 compared to control and sham groups; ap<0.05, aap<0.01 compared to isc+Aca10 mg/kg group; bp<0.05 compared to isc+ Aca25 mg/kg group; ≠p<0.05, ≠≠p<0.01 compared to ischemia-reperfusion group