Table 1.

Specificity profile of natural lectins.

Lectin name	Origin	Monosaccharide specificity a)	Preferred glycan structure	Refs.
Fungal lectins
AAL	Aleuria aurantia	Fuc	Fucα6GlcNAc (core Fuc), Fucα3(Galβ4) GlcNAc (Lex)	29
ABA	Agaricus bisporus	Gal, GlcNAc	Galβ3GalNAc, GlcNAc	30
ACG	Agrocybe cylindracea	Gal	Siaα3Galβ4GlcNAc	31
Plant lectins
ACA	Amaranthus caudatus	Gal	Galβ3GalNAc	32
ACL	Amaranthus caudatus	Gal	Galβ1‐3GalNAc	33
BPL	Bauhinia purpurea	Gal	Galβ3GalNAc, GalNAc	34
BS−I	Bandeiraea simplicifolia	Gal, GalNAc	αGal, αGalNAc	23b
ConA	Canavalia ensiformis	Man	High‐Man including Manα6(Manα3) Man	35
DBA	Dolichos biflorus	GalNAc	GalNAcα3GalNAc	36
DSA	Datura stramonium	GlcNAc	(GlcNAcβ4) n, triantennary, tetraantennary N‐glycans	37
ECA	Erythrina cristagalli	Gal	Galβ4GlcNAc	38
GNA	Galanthus nivalis	Man	High‐Man including Manα3Man	39
GSL−I−B4	Griffonia simplicifolia	Gal	α Gal	34
GSL−II	Griffonia simplicifolia	GlcNAc	Agalactosylated tri/tetra antennary glycans, GlcNAc	40
HHL	Hippeastrum Hybrid	Man	High‐Man including Mana3Man or Mana6Man	41
Jacalin	Artocarpus integrifolia	Gal	Galβ3GalNAc, αGalNAc (6O‐unsubstituted)	42
LCA	Lens culinaris	Fuc/Man	Fucα6GlcNAc, High‐Man	43
LEL	Lycopersicon esculentum	GlcNAc	(GlcNAcβ4) n, (Galβ4GlcNAc) n (polylactosamine)	44
LTL	Lotus tetragonolobus	Fuc	Fucα3(Galβ4) GlcNAc (Lex), Fucα2Galβ4GlcNAc (H‐type 2)	45
MPL	Maclura pomifera	GalNAc	αGalNAc	23b
NPA	Narcissus pseudonarcissus	Man	High‐Man including Manα6Man	41
PHA−E	Phaseolus vulgaris	Gal	N‐glycans with outer Gal and bisecting GlcNAc	46
PHA−L	Phaseolus vulgaris	Complex	Tri/tetra‐antennary complex‐type N‐glycan	46
PNA	Arachis hypogaea	Gal	Galβ3GalNAc	34
PSA	Pisum sativum	Fuc/Man	Fucα6GlcNAc, High‐Man	43
PTL−I	Psophocarpus tetragonolobus	GalNAc	α GalNAc	47
PWM	Phytolacca Americana	GlcNAc	(GlcNAcβ4) n	48
RCA−I	Ricinus communis	Gal	Galβ4GlcNAc	38
SBA	Dolichos biflorus	GalNAc	GalNAc, GalNAcα3Gal	34
SNA	Sambucus nigra	Sia	Siaα2‐6Gal/GalNAc	36
SSA	Sambucus sieboldiana	Sia	Siaα2‐6Gal/GalNAc	49
STL	Solanum tuberosum	GlcNAc	(GlcNAcβ) n, (GlcNAcβ4MurNAc) n (peptidoglycan backbone)	50
TJA−I	Tanthes japonica	Sia	Siaα2‐6Gal/GalNAc	51
UDA	Urtica dioica	GlcNAc	GlcNAcβ4GlcNAc, Man5∼ Man9	52
UEA−I	Ulex europaeus	Fuc	Fucα2Galβ4GlcNAc (H‐type 2)	53
VVA	Vicia villosa	GalNAc	α GalNAc, GalNAcα3Gal	54
WFA	Wisteria floribunda	GalNAc	GalNAcβ4GlcNAc, Galβ3(‐6) GalNAc	34

a) Fuc, fucose; Gal, galactose; GlcNAc, N‐acetyl‐D‐glucosamine; Man, mannose; GalNAc, N‐Acetyl‐D‐galactosamine; Sia, sialic acid