Table 3.
Comparison between current (line 1 in each row) and previous (line 2 in each row) cohorts about statements related to understanding of the PMRP. Higher numbers indicate better understanding.
| Statement | N | 1 | 2 | 3 | 4 | 5 | p-value |
|---|---|---|---|---|---|---|---|
| 1. The fact that the Personalized Medicine Research Project involves genetic research. | 49 913 |
2.0% 0.7% |
2.0% 1.3% |
12.2% 7.9% |
34.7% 20.2% |
49.0% 69.8% |
0.002 |
| 2. What the researchers are trying to find out in the Personalized Medicine Research Project. | 49 913 |
2.0% 1.1% |
2.0% 3.5% |
14.3% 21.1% |
46.9% 36.9% |
34.7% 37.1% |
0.750 |
| 3. How long you will be in the research study. | 46 909 |
8.7% 4.2% |
4.3% 9.5% |
23.9% 32.9% |
17.4% 24.3% |
45.7% 29.2% |
0.097 |
| 4. The procedures that you will undergo as part of the study. | 49 909 |
0.0% 3.3% |
6.1% 5.1% |
10.2% 22.2% |
36.7% 26.6% |
46.9% 42.7% |
0.177 |
| 5. Which of the procedures are experimental. | 46 897 |
0.0% 9.6% |
17.4% 11.5% |
23.9% 35.6% |
30.4% 22.5% |
28.3% 20.8% |
0.060 |
| 6. The possible risks and discomforts of participating in the Personalized Medicine Research Project. | 49 909 |
0.0% 3.9% |
6.1% 4.0% |
12.2% 17.9% |
36.7% 26.3% |
44.9% 48.0% |
0.834 |
| 7. The possible benefits to you of participating in the Personalized Medicine Research Project. | 49 909 |
4.1% 2.8% |
6.1% 3.2% |
14.3% 16.1% |
30.6% 31.2% |
44.9% 46.8% |
0.655 |
| 8. How your participation in the Personalized Medicine Research Project may benefit future patients. | 49 913 |
0.0% 0.7% |
0.0% 1.1% |
6.1% 5.9% |
20.4% 26.2% |
73.5% 66.2% |
0.293 |
| 9. The alternatives to participation in the Personalized Medicine Research Project. | 49 902 |
6.1% 7.4% |
4.1% 7.4% |
20.4% 25.6% |
20.4% 20.3% |
49.0% 39.2% |
0.137 |
| 10. How the confidentiality of my medical records will be protected under the Personalized Medicine Research Project. | 49 909 |
4.1% 2.4% |
0.0% 2.2% |
8.2% 12.5% |
18.4% 28.2% |
69.4% 54.7% |
0.062 |
| 11. Who will pay for treatment if you are injured or become ill as part of this research study. | 49 902 |
8.2% 8.3% |
12.2% 11.6% |
20.4% 31.5% |
28.6% 18.4% |
30.6% 30.0% |
0.507 |
| 12. Whom you should contact if you have questions or concerns about the Personalized Medicine Research Project. | 49 910 |
2.0% 4.3% |
8.2% 6.6% |
8.2% 21.0% |
28.6% 23.5% |
53.1% 44.6% |
0.126 |
| 13. The fact that participation in the Personalized Medicine Research Project is voluntary. | 49 914 |
0.0% 0.8% |
0.0% 0.3% |
2.0% 2.6% |
8.2% 10.3% |
89.8% 86.0% |
0.440 |
| 14. Overall, how well did you understand the Personalized Medicine Research Project when you signed the consent form. | 49 907 |
0.0% 0.8% |
0.0% 2.0% |
8.2% 16.3% |
51.0% 42.7% |
40.8% 38.1% |
0.246 |