Table 5.
Comparison between computer-based consenting (line 1 in each row) and traditional (line 2 in each row) groups related to understanding of the PMRP. Higher numbers indicate better understanding.
| Statement | N | 1 | 2 | 3 | 4 | 5 | p-value |
|---|---|---|---|---|---|---|---|
| 1. The fact that the Personalized Medicine Research Project involves genetic research. | 22 27 |
0.0% 3.7% |
0.0% 3.7% |
4.5% 18.5% |
45.5% 25.9% |
50.0% 48.1% |
0.411 |
| 2. What the researchers are trying to find out in the Personalized Medicine Research Project. | 22 27 |
0.0% 3.7% |
0.0% 3.7% |
9.1% 18.5% |
45.5% 48.1% |
45.5% 25.9% |
0.076 |
| 3. How long you will be in the research study. | 21 25 |
0.0% 16.0% |
0.0% 8.0% |
28.6% 20.0% |
14.3% 20.0% |
57.1% 36.0% |
0.081 |
| 4. The procedures that you will undergo as part of the study. | 22 27 |
0.0% 0.0% |
4.5% 7.4% |
0.0% 18.5% |
40.9% 33.3% |
54.5% 40.7% |
0.155 |
| 5. Which of the procedures are experimental. | 22 24 |
0.0% 0.0% |
4.5% 29.2% |
27.3% 20.8% |
40.9% 20.8% |
27.3% 29.2% |
0.259 |
| 6. The possible risks and discomforts of participating in the Personalized Medicine Research Project. | 22 27 |
0.0% 0.0% |
0.0% 11.1% |
9.1% 14.8% |
40.9% 33.3% |
50.0% 40.7% |
0.255 |
| 7. The possible benefits to you of participating in the Personalized Medicine Research Project. | 22 27 |
0.0% 7.4% |
0.0% 11.1% |
13.6% 14.8% |
36.4% 25.9% |
50.0% 40.7% |
0.198 |
| 8. How your participation in the Personalized Medicine Research Project may benefit future patients. | 22 27 |
0.0% 0.0% |
0.0% 0.0% |
4.5% 7.4% |
18.2% 22.2% |
77.3% 70.4% |
0.584 |
| 9. The alternatives to participation in the Personalized Medicine Research Project. | 22 27 |
0.0% 11.1% |
4.5% 3.7% |
13.6% 25.9% |
18.2% 22.2% |
63.6% 37.0% |
0.046 |
| 10. How the confidentiality of my medical records will be protected under the Personalized Medicine Research Project. | 22 27 |
0.0% 7.4% |
0.0% 0.0% |
4.5% 11.1% |
18.2% 18.5% |
77.3% 63.0% |
0.211 |
| 11. Who will pay for treatment if you are injured or become ill as part of this research study. | 22 27 |
0.0% 14.8% |
9.1% 14.8% |
22.7% 18.5% |
27.3% 29.6% |
40.9% 22.2% |
0.078 |
| 12. Whom you should contact if you have questions or concerns about the Personalized Medicine Research Project. | 22 27 |
0.0% 3.7% |
4.5% 11.1% |
9.1% 7.4% |
27.3% 29.6% |
59.1% 48.1% |
0.359 |
| 13. The fact that participation in the Personalized Medicine Research Project is voluntary. | 22 27 |
0.0% 0.0% |
0.0% 0.0% |
0.0% 3.7% |
9.1% 7.4% |
90.9% 88.9% |
0.803 |
| 14. Overall, how well did you understand the Personalized Medicine Research Project when you signed the consent form. | 22 27 |
0.0% 0.0% |
0.0% 0.0% |
0.0% 14.8% |
54.5% 48.1% |
45.5% 37.0% |
0.275 |