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. Author manuscript; available in PMC: 2020 Mar 2.
Published in final edited form as: Bioorg Med Chem. 2019 Mar 13;27(9):1795–1803. doi: 10.1016/j.bmc.2019.03.026

Figure 5. DABL compounds inhibit mouse polyoma virus.

Figure 5.

(A) A31 cells uninfected or infected with mouse MuPyV and treated with increasing concentrations (100 nM, 1.0 μM or 10 μM) of the indicated compounds. (B) Total RNA was isolated 24 hpi from cells treated with the indicated concentration of compound. Levels of MuPyV LT mRNA were determined by quantitative PCR and normalized to untreated cells. Shown is mean (± SD), data is cumulative from two independent experiments (n=4 per treatment condition). Statistical significance was determined by 2-way ANOVA (*, **, **** p<0.05, 0.01, 0.0001).