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. Author manuscript; available in PMC: 2020 Dec 24.
Published in final edited form as: Phys Med Biol. 2020 Jan 24;65(3):03LT01. doi: 10.1088/1361-6560/ab59f1

Figure 3.

Figure 3.

(a) Temporal changes of oxygen concentration ([3O2]) in a hypoxic radiation-induced fibrosarcoma (RIF) tumor on flank (red) and an oxygenated RIF tumor on shoulder (green) during Photofrin-mediated PDT for two representative mice. (b) Exponential tumor regrowth within two weeks follow up after PDT, and (c) Kaplan–Meier survival curves generated for tumor volumes ⩽100 mm3. The tumors with no Photofrin and no photoexcitation were considered as control (black line). The green and red curves and symbols show the oxygenated (on shoulder) and hypoxic (on flank) tumors, respectively.