Source	Search strategy	Hits retrieved
1. ALOIS (www.medicine.ox.ac.uk/alois) [Searched on 02 March 2015; up‐to‐date: 01 March 2015]	rivastigmine OR "SDZ ENA 713" OR exelon	Feb 2013: Jan 2014: 5 March 2015: 17
2. MEDLINE In‐process and other non‐indexed citations and MEDLINE Feb 2013: 1950‐present (OvidSP) Jan 2014: 1950‐present [24 January 2014] (OvidSP)	1. exp Dementia/ 2. Delirium, Dementia, Amnestic, Cognitive Disorders/ 3. dement*.mp. 4. alzheimer*.mp. 5. ("organic brain disease" or "organic brain syndrome").mp. 6. "benign senescent forgetfulness".mp. 7. (cerebr* adj2 deteriorat*).mp. 8. (cerebral* adj2 insufficient*).mp. 9. or/1‐8 10. Rivastigmin*.ti,ab. 11. exelon*.ti,ab. 12. (ENA or "SDZ ENA 713").ti,ab. 13. *Cholinesterase Inhibitors/ 14. or/10‐13 15. 9 and 14 16. controlled trial.pt. 17. controlled clinical trial.pt. 18. .ab. 19. placebo.ab. 20. drug therapy.fs. 21. randomly.ab. 22. trial.ab. 23. groups.ab. 24. or/16‐23 25. (animals not (humans and animals)).sh. 26. 24 not 25 27. 15 and 26 28. (2011* or 2012* or 2013*).ed. 29. 27 and 28	Feb 2013: 299 Jan 2014: 144
3. EMBASE Feb 2013: 1974‐2013 Feb 14 (OvidSP) Jan 2014: 1974‐2014 January 23 (OvidSP)	1. cognitive defect/ 2. dement*.mp. 3. alzheimer*.mp. 4. ("organic brain disease" or "organic brain syndrome").mp. 5. (cerebr* adj2 deteriorat*).mp. 6. (cerebral* adj2 insufficient*).mp. 7. Alzheimer disease/ 8. AD.ab. 9. or/1‐8 10. RIVASTIGMINE/ 11. rivastigmin*.ti,ab. 12. exelon*.ti,ab. 13. (ENA or "SDZ ENA 713").ti,ab. 14. or/10‐13 15. 9 and 14 16. controlled trial/ 17. controlled clinical trial/ 18. placebo.ab. 19. randomly.ab. 20. trial.ab. 21. ("double‐blind*" or "double‐mask*").ti,ab. 22. or/16‐21 23. 15 and 22 24. (2011* or 2012* or 2013*).em. 25. 23 and 24	Feb 2013: 135 Jan 2014: 79
4. PsycINFO Feb 2013: 1806‐February week 2 2013 (OvidSP) Jan 2014: 1806‐January week 3 2014 (OvidSP)	1. alzheimer*.mp. 2. ("organic brain disease" or "organic brain syndrome").mp. 3. (cerebr* adj2 deteriorat*).mp. 4. (cerebral* adj2 insufficient*).mp. 5. Alzheimer's Disease/ 6. AD.ab. 7. or/1‐6 8. rivastigmin*.ti,ab. 9. exelon*.ti,ab. 10. (ENA or "SDZ ENA 713").ti,ab. 11. or/8‐10 12. 7 and 11 13. (2011* or 2012* or 2013*).up. 14. 12 and 13	Feb 2013: 56 Jan 2014: 28
5. CINAHL (EBSCOhost) Feb 2013: all dates to February week 1 2013	S1 (MH "Dementia+")   S2 (MH "Delirium") or (MH "Delirium, Dementia, Amnestic, Cognitive Disorders") S3 (MH "Wernicke's Encephalopathy")   S4 TX dement*   S5 TX alzheimer*  S6 TX lewy* N2 bod*   S7 TX deliri*  S8 TX chronic N2 cerebrovascular   S9 TX "organic brain disease" or "organic brain syndrome"   S10 TX "normal pressure hydrocephalus" and "shunt*"   S11 TX "benign senescent forgetfulness"  S12 TX cerebr* N2 deteriorat*  S13 TX cerebral* N2 insufficient*   S14 TX pick* N2 disease S15 TX creutzfeldt or jcd or cjd   S16 TX huntington*  S17 TX binswanger*   S18 TX korsako*  S19 S1 or S2 or S3 or S4 or S5 or S6 or S7 or S8 or S9 or S10 or S11 or S12 or S13 or S14 or S15 or S16 or S17 or S18 S20 TX "cognit* impair*"  S21 TX "cognit* defect*"  S22 (MH "Cognition Disorders+")  S23 TX MCI  S24 TX ACMI  S25 TX ARCD  S26 TX SMC  S27 TX CIND  S28 TX BSF  S29 TX AAMI  S30 AB MD  S31 AB LCD  S32 AB QD OR "questionable dementia" S33 TX AACD  S34 TX MNCD  S35 TX "N‐MCI" or "A‐MCI" or "M‐MCI" S36 TX "preclinical AD"  S37 TX "pre‐clinical AD" S38 TX "preclinical alzheimer*" or "pre‐clinical alzheimer*"  S39 TX aMCI OR MCIa  S40 TX "CDR 0.5" or "clinical dementia rating scale 0.5"  S41 TX "GDS 3" OR "stage 3 GDS" S42 TX "global deterioration scale" AND "stage 3"  S43 TX "Benign senescent forgetfulness"  S44 TX "mild neurocognit* disorder*"  S45 TX prodrom* N2 dement* S46 TX "age‐related symptom*"  S47 TX cognit* N2 deficit* S48 TX cognit* N2 deteriorat* S49 TX cognit* N2 declin* S50 TX cognit* N2 degenerat* S51 TX cognit* N2 complain*  S52 TX cognit* N2 disturb*  S53 TX cognit* N2 disorder* S54 TX memory N2 episod* or TX memory N2 los* or TX memory N2 impair* or TX memory N2 complain* S55 TX memory N2 disturb* or TX memory N2 disorder* or TX cerebr* N2 impair* or TX cerebr* N2 los*  S56 TX cerebr* N2 complain* or TX cerebr* N2 deteriorat* or TX cerebr* N2 disorder* or TX cerebr* N2 disturb*  S57 TX mental* N2 declin* or TX mental* N2 los* or TX mental* N2 impair* or TX mental* N2 deteriorat*  S58 TX "pre‐clinical dementia" or TX "preclinical dementia"  S59 S20 or S21 or S22 or S23 or S24 or S25 or S26 or S27 or S28 or S29 or S30 or S31 or S32 or S33 or S34 or S35 or S36 or S37 or S38 or S39 or S40 or S41 or S42 or S43 or S44 or S45 or S46 or S47 or S48 or S49 or S50 or S51 or S52 or S53 or S54 or S55 or S56 or S57 or S58  S60 S19 or S59	Feb 2013: 50
6. Web of Science and conference proceedings Feb 2013: 1950 to Feb 14 2013 Jan 2014: 1950 to Jan 24 2014	Topic=(dement* OR alzheimer* OR "lewy bod*" OR DLB OR "vascular cognitive impairment*" OR FTD OF FTLD OR "cerebrovascular insufficienc*") AND Topic=(rivastigmin* OR exelon OR "SDZ ENA 713") AND Topic=(random* OR placebo OR "double‐blind*" OR trial OR RCT OR CCT) AND Year Published=(2011‐2013) Timespan=All Years. Databases=SCI‐EXPANDED, SSCI, A&HCI, CPCI‐S, CPCI‐SSH.	Feb 2013: 102 Jan 2014: 54
7. LILACS (BIREME) Feb 2013: all dates to 14 February 2013 Jan 2014: all dates to 24 January 2014	rivastigmine OR rivastigmine OR "SDZ ENA 713" OR exelon [Words]	Feb 2013: 9 Jan 2014: 3
8. CENTRAL (The Cochrane Library) Feb 2013: Issue 4 of 12, 2013 Jan 2014: Issue 1 of 12, 2014	#1 MeSH descriptor: [Dementia] explode all trees #2 MeSH descriptor: [Delirium] this term only #3 MeSH descriptor: [Wernicke Encephalopathy] this term only #4 MeSH descriptor: [Delirium, Dementia, Amnestic, Cognitive Disorders] this term only #5 dement* #6 alzheimer* #7 "lewy* bod*" #8 deliri* #9 "chronic cerebrovascular" #10 "organic brain disease" or "organic brain syndrome" #11 "normal pressure hydrocephalus" and "shunt*" #12 "benign senescent forgetfulness" #13 "cerebr* deteriorat*" #14 "cerebral* insufficient*" #15 "pick* disease" #16 creutzfeldt or jcd or cjd #17 huntington* #18 binswanger* #19 korsako* #20 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18 or #19 #21             rivastigmin* or exelon* or "SDZ ENA 713" #22 #20 and #21 from 2011 to 2013, in Trials	Feb 2013: 7 Jan 2014: 12
9. Clinicaltrials.gov (www.clinicaltrials.gov) ‐ all dates	rivastigmine OR exelon OR "SDZ ENA 713" | Interventional Studies | dementia OR alzheimer OR alzheimers OR lewy OR vascular cognitive impairment | Adult, Senior | received from 01/01/2011 to 02/15/2013	Feb 2013: 16 Jan 2014: 0
10. ICTRP Search Portal (http://apps.who.int/trialsearch) [includes: Australian New Zealand Clinical Trials Registry; ClinicalTrilas.gov; ISRCTN; Chinese Clinical Trial Registry; Clinical Trials Registry – India; Clinical Research Information Service – Republic of Korea; German Clinical Trials Register; Iranian Registry of Clinical Trials; Japan Primary Registries Network; Pan African Clinical Trial Registry; Sri Lanka Clinical Trials Registry; The Netherlands National Trial Register] ‐ all dates	Advanced search: (rivastigmine OR exelon OR "SDZ ENA 713" | Interventional Studies) AND (received from 01/01/2011 to 02/15/2013)	Feb 2013: 136 Jan 2014: 2
TOTAL before de‐duplication		Feb 2013: 922 Jan 2014: 327
TOTAL after de‐dupe and first assess		Feb 2013: 36 Jan 2014: 24 March 2015: 17