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. 2020 Feb 28;10(2):e035595. doi: 10.1136/bmjopen-2019-035595

Table 5.

Mortality of TB-exposed children compared with TB-unexposed children by timing of BCG and sex

MR per 1000 PYRS HR
(deaths/PYRS) (95% CI)
All children
Neonatal BCG
 TB-exposed 12.2 (30/2462) 1.11 (0.77 to 1.61)
 TB-unexposed 13.5 (533/39 608) Ref
No neonatal BCG
 TB-exposed 35.2 (13/369) 1.93 (1.10 to 3.41)
 TB-unexposed 22.8 (157/6880) Ref
Boys
Neonatal BCG
 TB-exposed 8.5 (11/1288) 0.77 (0.42 to 1.41)
 TB-unexposed 13.6 (275/20 166) Ref
No neonatal BCG
 TB-exposed 35.6 (7/197) 1.98 (0.91 to 4.28)
 TB-unexposed 23.0 (80/3478) Ref
Girls
Neonatal BCG
 TB-exposed 16.2 (19/1174) 1.50 (0.94 to 2.39)
 TB-unexposed 13.3 (258/19 442) Ref
No neonatal BCG
 TB-exposed 34.7 (6/173) 1.90 (0.83 to 4.35)
 TB-unexposed 22.6 (77/3402) Ref

All HRs were obtained from Cox-proportional hazards models with age as underlying age, allowing different baseline hazards by sex and birth location.

Adjusted HR are not presented as no baseline factor changed the estimates by more than 5%.

MR, mortality rate; PYRS, person years; TB, tuberculosis.