Skip to main content
. Author manuscript; available in PMC: 2021 Mar 10.
Published in final edited form as: J Control Release. 2020 Jan 7;319:428–437. doi: 10.1016/j.jconrel.2020.01.011

Fig. 4. AFL-assisted 3-day sustained AZT delivery in vivo.

Fig. 4

A-C. Lateral back skin of BALB/c mice was exposed to AFL (2.5 mJ5/%) followed by topical application of powder AZT-coated reservoir patches at 1:1 (A), 1:2.5 (B), or 1:5 mixing ratio (C). A small amount of blood (~25 μl) was collected before delivery and 1, 3, 6, 9, 12, 16, 20, 26, 32, 36, 42, 48, 54, 60, and 72 hours after delivery to measure serum AZT levels. D. BALB/c mice were subjected to oral delivery of 0.32 mg AZT. A small amount of blood (~25 μl) was collected before delivery and 0.5, 1, 1.5, 2, 2.5, 3 and 6 hours after delivery to measure serum AZT levels. n=6