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. Author manuscript; available in PMC: 2020 Mar 2.
Published in final edited form as: J Leukoc Biol. 2019 Feb 28;106(1):83–93. doi: 10.1002/JLB.3MIR0918-354R

TABLE 1.

LncRNAs in Innate Immune Cell Function

LncRNA Species Function Reference
Lnc-DC Hu, Ms Binds to and inhibits dephosphorylation of STAT3, subsequently promoting expression of DC-associated genes including CD40 and CD80 31
LncHSC1/2 Hs Drives myeloid cell differentiation 52
HOTAIRM1 Hu RA-induced lncRNA necessary for in vitro differentiation of monocyte lines into granulocytes; promotes CD11b and CD18 expression 55
Morrbid Ms Recruits the polycomb repressive complex to the Bcl2l11 promoter to support survival of short lived myeloid cell populations 22
Rroid Ms Regulates STAT5 deposition at the Id2 locus via retention of 3D chromatin architecture in a lncRNAindependent manner 27
Lnckdm2b Ms Supports ILC3 homeostatic proliferation via interaction with Satb1 and NURF to induce expression of Zfp292 and Bptf 83