. Author manuscript; available in PMC: 2020 Mar 2.

Published in final edited form as: J Leukoc Biol. 2019 Feb 28;106(1):83–93. doi: 10.1002/JLB.3MIR0918-354R

TABLE 4.

Virally Encoded LncRNAs

LncRNAs	Virus	Phenotype	Reference
PAN RNA	KSHV	Interacts with IRF4 preventing correct localization to immune loci; binds to JMDJ3, UTX, MLL to mediate the switch from latent to lytic infection	^75,76
sfRNA	Flavivirus	Generated by XRN1 degradation of flaviviral genomes; inhibits the function of XRN1, TRIM25 and the CAPRIN/G3BP1/G3BP2 complex	^{77–79,81,82}
LAT	HSV-1, HSV-2	The only transcript expressed during latent infection; required to maintain latency	^92,93
Beta2.7	HCMV	Prevents host cell apoptosis via interactions with mitochondrial complex 1	⁹⁴