Skip to main content
. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Neurobiol Dis. 2020 Jan 21;137:104759. doi: 10.1016/j.nbd.2020.104759

Figure 5.

Figure 5.

Ictal and interictal cardiac abnormalities in neuron-specific Kcna1 cKO mice. A, Simultaneous EEG-ECG recording showing bradycardia (between the two arrows) during a seizure in a cKO mouse. B, Simultaneous EEG-ECG recording showing multiple AV blocks (arrowheads), which appear as skipped heart beats, during a seizure in a cKO mouse. C, Quantification of the frequency of skipped heart beats (e.g., AV blocks or sinus pauses) during the day and night and overall (day and night combined) in WT, hemizygous Syn1-Cre (Cre), compound heterozygous Kcna1 floxed/null (fl/−), and neuron-specific Kcna1 cKO mice (cKO). D, Quantification of mean heart rate by genotype during the day and night and overall (day and night combined).