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Y-family polymerases. Unique lesion bypass mechanisms of a templating lesion and incoming nucleotide are indicated (white sticks). a human Pol η shown in surface (green; 3MR3) b human Pol ι shown in cartoon (green; 2DPJ) c human Pol κ shown in surface with indicated catalytic core (green), PAD (yellow), and N-clasp (cyan) (4U7C) d yeast Rev1 shown in cartoon with undamaged templating guanine (green; 2AQ4), overlayed with damaged guanine template (white) and residues (cyan sticks; 5WM1)
