Figure 3.

The dynamic changes of core liver functions and hepatic cell types. (A) Proteins involved in the eight core liver functions were retrieved from the common knowledge databases (KEGG, Reactome, and Gene Ontology) and their temporal expression patterns were mapped along the developmental time scale. (B) Relative expression levels of five hepatic cell types represented by their selective markers or cell-type-specific proteins. (C) A summary of the eight liver functions and the expressions of the five hepatic cell types on the development time scale.