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. Author manuscript; available in PMC: 2020 Mar 2.
Published in final edited form as: Lancet Oncol. 2019 Jan 29;20(3):361–370. doi: 10.1016/S1470-2045(18)30750-2

Table 4:

Surrogate threshold effects in the full and reduced sets, according to the expected number of deaths in a future randomised trial

Pre-specified
full set
(12 contrasts)
Post-hoc
reduced set
(11 contrasts)
100 0·56 0·59
200 0·66 0·69
400 0·75 0·77
800 0·81 0·83

Numbers are HR for disease-free survival.