Table 2.
Overall resistance rate of Klebsiella pneumoniae to various antimicrobials
| Subgroups | No. of events/studies | Prevalence of drug resistance, % (CI) | Heterogeneity test | |
|---|---|---|---|---|
| I2 (%) | p value | |||
| Overall resistant to amikacin | 11 | 40.8 (31.9–50.4) | 93.7 | < 0.001 |
| Overall resistant to aztreonam | 9 | 73.3 (59.9–83.4) | 97.4 | < 0.001 |
| Overall resistant to ceftazidime | 10 | 75.7 (65.4–83.6) | 90.5 | < 0.001 |
| Overall resistant to ciprpfloxacin | 11 | 59.8 (48.6–70.1) | 96.4 | < 0.001 |
| Overall resistant to colistin | 5 | 2.9 (1.8–4.4) | 0.0 | 0.5250 |
| Overall resistant to cefotaxime | 8 | 79.2 (68.0–87.2) | 93.8 | < 0.001 |
| Overall resistant to cefepime | 8 | 72.6 (57.7–83.8) | 96.9 | < 0.001 |
| Overall resistant to gentamicin | 9 | 58 (49.2–66.3) | 89.7 | < 0.001 |
| Overall resistant to imipenem | 10 | 65.6 (30.8–89.0) | 99.6 | < 0.001 |
| Overall resistant to levofloxacin | 6 | 54.1 (36.0–71.2) | 92.7 | < 0.001 |
| Overall resistant to meropenem | 11 | 62.7 (31.1–86.2) | 99.5 | < 0.001 |
| Overall resistant to trimethoprim_sulfamethoxazole | 7 | 58.2 (35.5–77.9) | 98.8 | < 0.001 |
CI, confidence interval; n, number of events (drug resistance); N, total number of Klebsiella pneumoniae from the included studies