Comparison 2. Aminoglycoside plus penicillin or ampicillin versus any other regimen.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Treatment failure	2		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 Aminoglycoside plus penicillin versus gentamycin/clindamycin	1	200	Risk Ratio (M‐H, Random, 95% CI)	2.57 [1.48, 4.46]
1.2 Aminoglycoside plus ampicillin versus piperacillin/tazobactam	1	56	Risk Ratio (M‐H, Random, 95% CI)	0.56 [0.15, 2.03]
2 Severe complication	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 Aminoglycoside plus penicillin versus gentamycin/clindamycin	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	0.11 [0.01, 2.04]
2.2 Amnioglycoside plus ampicillin versus piperacillin/tazobactam	1	56	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Wound infection	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 Aminoglycoside plus penicillin versus gentamycin/clindamycin	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	0.5 [0.22, 1.12]
3.2 Aminoglycoside plus ampicillin versus piperacillin/tazobactam	1	56	Risk Ratio (M‐H, Fixed, 95% CI)	2.44 [0.13, 44.57]
4 Allergic reaction	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
4.1 Aminoglycoside plus penicillin versus gentamicin/clindamycin	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	1.0 [0.14, 6.96]
4.2 Aminoglycoside plus ampicillin versus piperacillin/tazobactam	1	56	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
5 Diarrhea	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
5.1 Aminoglycoside plus penicillin versus gentamicin/clindamycin	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	5.0 [0.24, 102.85]
5.2 Aminoglycoside plus ampicillin versus piperacillin/tazobactam	1	56	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]